Cancer of Unknown Primary (CUP)
Cancer of Unknown Primary (CUP): Overview
Cancer of Unknown Primary (CUP) is a rare condition where cancer cells are found, but their origin remains unidentified. It accounts for 2–5% of all cancers and presents diagnostic and treatment challenges.
Symptoms
Symptoms vary based on the affected areas and include:
- Unexplained weight loss
- Fatigue
- Pain or swelling in specific areas
- Persistent cough or breathing difficulty
Diagnosis
Diagnosing CUP involves:
- Imaging Tests: CT, MRI, or PET scans
- Biopsy: Studying tissue samples
- Molecular Testing: Identifying genetic markers
- Blood Tests: Checking for tumor markers
Treatment
Treatment focuses on managing the cancer’s spread:
- Chemotherapy: Targets cancer cells systemically
- Radiation Therapy: Reduces tumor size and symptoms
- Targeted Therapy: Tailored drugs based on genetic profiling
- Immunotherapy: Strengthens the immune system
- Supportive Care: Improves quality of life
Coping and Outlook
CUP prognosis depends on the spread and response to treatment. Advances in molecular testing are improving outcomes. Support groups and counseling can help patients manage emotional and physical challenges.